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Dr. Hannah Marchant

Dr. Hannah Marchant

St George’s Hospital

Dr. Hannah Marchant graduated with Honours from King’s College London in 2023 and achieved her MFDS from the Royal College of Surgeons of England in 2024. She is currently a Dental Core Trainee in Oral and Maxillofacial Surgery at St George’s Hospital, London. With diverse clinical experience across general practice, restorative dentistry, orthodontics, and oral surgery, she is skilled in managing complex, multidisciplinary cases. An active academic contributor, she has published research and presented at national and international conferences.

United Kingdom

Abstracts

2026

A rare case of chronic myeloid leukaemia manifesting as uncontrolled post-extraction haemorrhage

Post-operative bleeding is a recognised complication following dental extraction, particularly in patients with underlying systemic risk factors. However, persistent haemorrhage may occasionally be the first clinical manifestation of an undiagnosed haematological disorder.

This presentation explores a rare case of a 39-year-old male being diagnosed with chronic myeloid leukaemia (CML) after persistent post-extraction bleeding. The patient attended the Emergency Department with uncontrolled bleeding eight days after surgical extraction of a lower third molar. Despite repeated local haemostatic measures, including socket packing, suturing, bipolar diathermy, and tranexamic acid therapy, haemorrhage recurred. Blood tests revealed marked leukocytosis, anaemia, and thrombocytopenia, prompting urgent haematology referral. Bone marrow biopsy confirmed chronic-phase CML with BCR-ABL positivity. The patient responded well to oral Dasatinib therapy (a tyrosine kinase inhibitor) and demonstrated a rapid haematological response, with normalisation of white cell and platelet counts, and haemoglobin concentration, within four weeks and a subsequent major molecular response.

This case highlights the importance of recognising atypical post-operative bleeding as a potential indicator of underlying systemic disease. Prompt investigation and multidisciplinary management can facilitate early diagnosis and treatment of haematological malignancies, ultimately improving patient outcomes.